Science

Peer-reviewed publications

  1. Regl C, Wohlschlager T, Esser-Skala W, Wagner I, Samonig M, Holzmann J, and Huber CG.
    Dilute-and-shoot analysis of therapeutic monoclonal antibody variants in fermentation broth: a method capability study.
    MAbs 11(3), 569–582 (2019). 
  2. Debela M, Magdolen V, Skala W, Elsässer B, Schneider EL, Craik CS, Biniossek ML, Schilling O, Bode W, Brandstetter H, and Goettig P.
    Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.
    Sci. Rep. 8(1), 10705 (2018). 
  3. Wohlschlager T, Scheffler K, Forstenlehner IC, Skala W, Senn S, Damoc E, Holzmann J, and Huber CG.
    Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals.
    Nat. Commun. 9(1), 1713 (2018). 
  4. Skala W, Wohlschlager T, Senn S, Huber GE, and Huber CG.
    MoFi – A software tool for annotating glycoprotein mass spectra by integrating hybrid data from the intact protein and glycopeptide level.
    Anal. Chem. 90(9), 5728–5736 (2018).
  5. Guo S, Skala W, Magdolen V, Briza P, Biniossek ML, Schilling O, Kellermann J, Brandstetter H, and Goettig P.
    A single glycan at the 99-loop of human kallikrein-related peptidase 2 regulates activation and enzymatic activity.
    J. Biol. Chem. 291(2), 593–604 (2016). 
  6. Skala W, Utzschneider DT, Magdolen V, Debela M, Guo S, Craik CS, Brandstetter H, and Goettig P.
    Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.
    J. Biol. Chem. 289(49), 34267–34283 (2014). 
  7. Guo S, Skala W, Magdolen V, Brandstetter H, and Goettig P.
    Sweetened kallikrein-related peptidases (KLKs): Glycan trees as potential regulators of activation and activity.
    Biol. Chem. 395(9), 959–976 (2014). 
  8. Skala W, Goettig P, and Brandstetter H.
    Do-it-yourself histidine-tagged bovine enterokinase: A handy member of the protein engineer’s toolbox.
    J. Biotechnol. 168(4), 421–425 (2013). 

Theses

  1. Organisation des Austrian Proteomics and Metabolomics Research Symposium 2019.
    Final thesis (supervisor: Sabine Reithofer-Reinhardt), SMBS, 2019. 
  2. Die Lösung des restringierten Steinerbaum-Problems mittels lokaler Suchverfahren.
    Bachelor thesis (supervisor: Friedhelm Kulmann), FernUniversität in Hagen, 2015. 
  3. Biochemical and structural characterization of human kallikrein-related peptidase 2 activated by do-it-yourself histidine-tagged bovine enterokinase.
    PhD thesis (supervisors: Hans Brandstetter and Peter Goettig), University of Salzburg, 2014. 
  4. Putative macaque and orangutan homologues of tripeptidyl-peptidase II underline the importance of its C-terminal part for enzymatic activity and proper oligomerization.
    Master thesis (supervisor: Hans Brandstetter), University of Salzburg, 2010. 
  5. Crystallization: From art to science.
    Bachelor thesis (supervisor: Hans Brandstetter), University of Salzburg, 2008.
  6. Determining the current-voltage characteristic: An electrophysiological study on Aquaporin-6.
    Bachelor thesis (supervisor: Peter Pohl), Johannes Kepler University Linz, 2007.

Software

  1. The pgfgantt package v5.0.
    LaTeX package, 2018 (CTAN).
  2. The pgfmolbio package v0.21.
    LaTeX package, 2013 (CTAN).
  3. The cpssp package v1.0.
    LaTeX package, 2009 (CTAN).

Trivia

I also wrote about 2300 pages of scripts for approximately 20 courses I attended during my academic studies. These texts constitute six formidable volumes of Collected Works that rest on my bedroom shelf.

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